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This page lists an index of all videos contained in the library.

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Cancer Biology

  • Cox, Adrienne – Oncogenes and Tumor Suppressor Genes: A Primer, seminar May 2017
  • Der, Channing – Targeting “Undruggable” RAS: Know Your Enemy, seminar November 2018
  • Emanuele, Michael – Ubiquitin Signaling in Cell Cycle and Cancer, seminar May 2019
  • Lopez-Berestein, Gabriel – Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells, seminar March 2018
  • Mieczkowski, Piotr – Cancer Genomics, seminar September 2016
  • Perou, Charles – Cancer Genomics, seminar June 2018
  • Schnitzer, Jan – Overcoming Key Barriers to Rapidly Penetrate, Image and Destroy Solid Tumors, seminar October 2017
  • Vincent, Benjamin – Mile High Overview of Immunology, seminar August 2016

2019 Targeted Delivery Workshop

  • Anselmo, Aaron – Delivery Strategies for the Microbiome, Targeted Delivery Workshop 2019
  • Hingtgen, Shawn – The Challenge of Treating Glioblastoma, Targeted Delivery Workshop 2019
  • Liu, Rihe – Tumor-Specific Surface Antigens, Targeted Delivery Workshop 2019

Types of Nanoformulations

2016 Carolina Nanoformulation Workshop

  • Ainslie, Kristy – Vaccine Delivery Using Nanoparticles, Carolina Nanoformulation Workshop 2016
  • Batrakova, Elena – Exosomes, Carolina Nanoformulation Workshop 2016
    Gu, Zhen – Smart Systems for Protein Delivery, Carolina Nanoformulation Workshop 2016
  • Haynes, Matt – Liposomes and Lipid-Stabilized Nanoprecipitates, Carolina Nanoformulation Workshop 2016
  • Hickey, Tony – PLGA Poly(lactic-co-glycolic acid) Micro/Nanoparticles, Carolina Nanoformulation Workshop 2016
  • Kabanov, Alexander – Polymeric Micelles, Carolina Nanoformulation Workshop 2016
  • Kabanov, Alexander – Polymer-Protein Conjugates and Nanozymes for CNS Delivery, Carolina Nanoformulation Workshop 2016
  • Kataoka, Kazunori – Polyion Complex (PIC) Micelles, Carolina Nanoformulation Workshop 2016
  • Lai, Sam – Mucus-penetrating Nanoparticles, Carolina Nanoformulation Workshop 2016
  • Luft, Chris – PRINT (Particle Replication in Non-Wetting Templates) Nanoparticles: Development, Optimization, and Biomedical Applications of PRINT Technology, Carolina Nanoformulation Workshop 2016
  • Sokolsky, Marina – Theranostic Inorganic Nanoparticles, Carolina Nanoformulation Workshop 2016

2017 Carolina Nanoformulation Workshop

  • Anderson, Daniel – Nanoparticulate Gene Therapy and Gene Editing: An Approach to siRNA Delivery, Carolina Nanoformulation Workshop 2017
  • Armstead, Andrea – The NanoAssembler Technology, Carolina Nanoformulation Workshop 2017
  • Bronich, Tatiana – Nanogels, Carolina Nanoformulation Workshop 2017
  • Benhabbour, Rahima – Long Acting Nanoformulations: Advantages, Limitations, and Applications, Carolina Nanoformulation Workshop 2017
  • Jiang, Wenlei – Characterization of Nanomaterials, Carolina Nanoformulation Workshop 2017
  • Prud’homme, Robert – Nanoparticle Formation and Block-Copolymer-Directed Rapid Precipitations: Flash Nanoprecipitation, Carolina Nanoformulation Workshop 2017
  • Riffle, Judy – Design of Materials and Polymers for Drug Delivery, Carolina Nanoformulation Workshop 2017
  • Rodgers, Zach – Lactic and Glycolic Acid (PLGA) Based Polymers for Drug Delivery and Vaccine Formulations, Carolina Nanoformulation Workshop 2017
  • Ting, Jenny – Nanoparticles as Vaccines – Immunomodulation by Nanoparticles, Carolina Nanoformulation Workshop 2017
  • Wang, Andy – Lactic Acid, Glycolic Acid, and Acid Based Polymers, Carolina Nanoformulation Workshop 2017

2019 Targeted Delivery Workshop

  • Alexander Kabanov – Super-High Capacity Polymeric Micelles for Cancer Therapeutics, Targeted Delivery Workshop 2019

Seminars

  • Bogdanov, Alexei – Molecular Imaging of Vascular Wall Inflammation, seminar November 2015
  • Bradbury, Michelle – Targeted Ultrasmall Particle Imaging Platforms as Next-Generation Treatment Tools for Drug Delivery and Induction of Cell Death, seminar April 2018
  • Day, Emily – Engineering nanoparticle architecture to enable high precision cancer therapy, seminar November 2018
  • Hammond, Paula – Functional Modular Nanomaterials for Strategic Delivery of Combination Therapies, seminar March 2017
  • Hubbell, Jeffrey – Materials and Protein Engineering for Modulating Immunity and Tolerance, seminar May 2015
  • Kataoka, Kazunori – Block Copolymer Micelles as Smart Nanocarriers for Targeted Drug Delivery, seminar April 2014
  • Lanza, Gregory – Contact-Facilitated Drug Delivery of Lipase-Labile Prodrugs with Targeted Lipid-based Nanotherapies, seminar April 2016
  • Mirkin, Chad – Liposomal Spherical Nucleic Acids: A New Approach to Immunomodulatory Therapies, seminar May 2015
  • Sen Gupta, Anirban – Bioinspired Nanomaterials for Vascular Interface Applications: Hemocompatibility, Hemostasis, and Targeted Drug Delivery, seminar September 2018
  • Riffle, Judy – Core-Shell Nanoparticles for Dual Drug Delivery and Bio-imaging, seminar February 2013
    Veiseh, Omid – Immune Modulatory Biomaterials for Cell-Based Therapies, seminar May 2019
  • Yang, Lily – Theranostic Nanoparticles for Precision Oncology, seminar November 2016

 

Pharmacokinetics and Pharmacodynamics (PK/PD)

2016 Carolina Nanoformulation Workshop

  • Hingtgen, Shawn – Stem Cell Mediated Drug Delivery and Imaging, Carolina Nanoformulation Workshop 2016
  • Lanza, Greg – Contact-Facilitated Drug Delivery of Lipase-Labile Prodrugs with Targeted Lipid-Based Nanotherapies, seminar April 2016
  • Parrott, Matt – Nanoradiopharmaceuticals: Therapy and Imaging, Carolina Nanoformulation Workshop 2016
  • Zamboni, Bill – Bi-directional Interaction Between the Mononuclear Phagocyte System and Nanoparticles in Patients and Preclinical Models, Carolina Nanoformulation Workshop 2016
  • Zamboni, Bill – Pharmacokinetics and Pharmacodynamics of Nanoparticle Agents, Carolina Nanoformulation Workshop 2016

2017 Carolina Nanoformulation Workshop

  • Banks, Bill – Drugs and Biomolecules Delivery to the Central Nervous System, Carolina Nanoformulation Workshop 2017
  • Kataoka, Kazunori – Nanoparticles and Tumor Penetration, Carolina Nanoformulation Workshop 2017
  • Santos, Luis – Preclinical Development of Nanoformulations and Scale-Up Considerations, Carolina Nanoformulation Workshop 2017
  • Senter, Peter – Antibody Drug Conjugates, Carolina Nanoformulation Workshop 2017
  • Senter, Peter – Potent Antibody-Based Conjugates for Cancer Therapy, Carolina Nanoformulation Workshop 2017
  • Zamboni, Bill – Pharmacokinetics and Biodistribution, Carolina Nanoformulation Workshop 2017

2019 Targeted Delivery Workshop

  • Sam Lai – Characterizing and Overcoming the Adaptive Immune Response to Synthetic Materials, Targeted Delivery Workshop 2019
  • Cao, Carter – Physiologically-based Pharmacokinetic Models for Nanoparticles and Protein Drugs, Targeted Delivery Workshop 2019

Seminars

  • Sahay, Guarav – Boosting Intracellular Nucleic Acid Delivery, seminar April 2018
  • Zamboni, Bill – Pharmacokinetics and Biodistribution Considerations in Nanodelivery, seminar June 2018
  • Zamboni, Bill – Pharmacokinetics and Pharmacodynamics of Nanoparticle Agents, seminar September 2016

 

Computer and Animal Models for Evaluating Efficacy of Nanoformulations

2016 Carolina Nanoformulation Workshop

  • Darr, David – Genetically-Engineered Mouse Models, Carolina Nanoformulation Workshop 2016
  • Tropsha, Alex – Chemoinformatics in Drug Delivery: Computer Modeling of Nanomaterials and Liposome-Based Drug Delivery Systems, Carolina Nanoformulation Workshop 2016

2017 Carolina Nanoformulation Workshop

  • Abramov, Yuriy – Computational Landscape of Pharmaceutical Drug Development, Carolina Nanoformulation Workshop 2017
  • Tropsha, Alex – Computer Modeling of Drug Delivery Systems, Carolina Nanoformulation Workshop 2017

Regulatory Considerations for Nanoformulations

2016 Carolina Nanoformulation Workshop

  • Alakhov, Valery – GRAS Components in Nanoformulations and Related (505)(b)(2) Opportunities, Carolina Nanoformulation Workshop 2016
  • Bulsara, Pallav – Novel Particulate Delivery Systems and Potential Chemistry Manufacturing and Control (CMC) Development Challenges, Carolina Nanoformulation Workshop 2016
  • Gaspar, Rogério – General Safety Considerations: Cellular/Tissue Uptake and Retention, Clearance From Tissue and Blood, and Administration Route-Specific Safety Considerations, Carolina Nanoformulation Workshop 2016
  • Gaspar, Rogério – Regulatory Considerations for Nanoformulations and Nanomedicines, Carolina Nanoformulation Workshop 2016
  • Patri, Anil – Physicochemical Characterization of Nanoparticle Therapeutics and Diagnostic Agents, Carolina Nanoformulation Workshop 2016
  • Wang, Andy – Clinical Nanomedicine: Success and Failure Stories, Carolina Nanoformulation Workshop 2016

2017 Carolina Nanoformulation Workshop

  • Alakhov, Valery – Innovative Pharmaceutical Ingredients and GRAS Components in Nanoformulations and Related (505)(b)(2) Opportunities, Carolina Nanoformulation Workshop 2017
  • Gaspar, Rogério – General Safety Considerations: Cellular/Tissue Uptake and Retention, Clearance From Tissue and Blood, and Administration Route-Specific Safety Considerations, Carolina Nanoformulation Workshop 2017
  • Gaspar, Rogério – Regulatory Considerations for Nanoformulations and Nanomedicines, Carolina Nanoformulation Workshop 2017

Clinical and Translational Aspects

2017 Carolina Nanoformulation Workshop

  • Alakhov, Valery – Technology Transfer from Bench to Bedside, Carolina Nanoformulation Workshop 2017

2018 Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop

  • Amelio, Antonio – Optical Imaging and Bioluminescent-Fluorescent BRET reporters, Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018
  • Hahn, Klaus – Biosensors and Non-Channel Optogenetics, Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018
  • Hyslop, Brian – Cancer Imaging using Body MRI/CT for Diagnosis, Staging, and Evaluation of Treatment Response, Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018
  • Lalush, David – Quantitative Imaging Methods in PET, MR, and CT, Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018
  • Lee, Yueh – Clinical Translation of Nanotechnology Relevant Novel Imaging Modalities (PET/MR and x-nuclei MRI), Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018
  • Li, Zibo – Development of PET Imaging Agents and Their Clinical Application, Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018
  • Oldan, Jorge – Clinical Use of PET and Emerging Tracers, Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018
  • Wu, Guorong – Accurate Image Guided Radiation Therapy for Lung Cancer Treatment, Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018
  • Yuan, Hong – Molecular Imaging of Cancer Treatment Response, Cancer Imaging and Non-Invasive Monitoring of Treatment Responses Workshop, September 2018

2019 Core Facilities Workshop

  • Bailey, Sean – Mouse Phase 1 Unit, Core Facilities Workshop, March 2019
    Beltran, Adriana – Human Pluripotent Stem Cells Core Facility, Core Facilities Workshop, March 2019
  • Gololobova, Olesia – Nanomedicines Characterization Core Facility, Core Facilities Workshop, March 2019

2019 Targeted Delivery Workshop

  • Shen, Colette – Targeting the Tumor and Microenvironment with Radiotherapy, Targeted Delivery Workshop 2019
  • Wang, Andy – Targeted Therapy Using Radiotherapy as Guidance, Targeted Delivery Workshop 2019

Seminars

  • Caster, Joe – Interpreting Clinical Trials, seminar May 2016
  • Caster, Joe – Preclinical Study Design, seminar May 2016
  • Chang, Sha – Newly Emerging Nanotechnology-Based X-ray Techniques for Cancer Imaging and Therapy, seminar May 2019
  • Dotti, Gianpietro – CAR-T Cells from the Bench to Clinical Application, seminar May 2018
  • Fisher, Nancy – Introduction to the UNC Flow Cytometry Core Facility, seminar June 2019
  • Fokin, Valery – Chemical Tools for Deciphering Biological Complexity, seminar May 2019
  • Frye, Stephen – Academic drug discovery and chemical biology, seminar April 2019
  • Gudkov, Andrei – Senescent Cells: Mammalian Aging Drivers or In Vitro Laboratory Effect? seminar March 2019
  • Hathaway, Nate – Drug discovery techniques, seminar April 2019
  • Koblansky, Alicia – Targeted Therapies in Cancer Biology: From Discovery to Production, seminar April 2018
  • Lee, Carrie – Planning for and Administering Clinical Trials, seminar March 2019
  • Lee, Michael – Drug Development and the Transition from Preclinical Research to Early Phase Clinical Trials, seminar January 2019
  • Malikowski, Marie – Drug Development, Clinical Trials, and Regulations, seminar January 2019
  • Moon, James – Nanomaterials for combination cancer immunotherapy, seminar April 2019
  • Pecot, Chad – What Scientists Can Learn From Clinical Trials in Cancer, seminar June 2016
  • Stern, Stephan – Challenges in Evaluation of Nanomedicine Pharmacokinetics and Generic Bioequivalence, seminar November 2017
  • Weaver, Mark – Rigor and Reproducibility, seminar June 2018

Informatics and Statistics

  • Moore, Dominic – Fundamental Statistical Concepts for Researchers, seminar August 2016

 

Recorded Lab Demonstrations

2016 Carolina Nanoformulation Workshop

  • Haynes, Matt – Remote Loading of Permeable Weak Bases into Liposomes, Carolina Nanoformulation Workshop 2016
  • Haynes, Matt – Preparation of Lipid Calcium Phosphate, Carolina Nanoformulation Workshop 2016
  • Luft, Chris – Drug-Loaded Particle Replication in Non-Wetting Templates Nanoparticles, Carolina Nanoformulation Workshop 2016
  • Sokolsky, Marina – Preparation of PLGA/PLGA-PEG Drug-Loaded Nanoparticles, Carolina Nanoformulation Workshop 2016
  • Sokolsky, Marina – Preparation of Polymeric Micelles by the Thin Film Hydration Method, Carolina Nanoformulation Workshop 2016

2017 Carolina Nanoformulation Workshop

  • Prud’homme, Robert – Flash NanoPrecipitation Demonstration, Carolina Nanoformulation Workshop 2017

 

Self-Paced Modules

  • Ainslie, Kristy – Vaccine Delivery Using Nanoparticles
  • Banks, Bill – Drugs and Biomolecules Delivery to the Central Nervous System
  • Bulsara, Pallav – Lipid Nanoparticles and CMC Development Challenges
  • Cox, Adrienne – Oncogenes and Tumor Suppressor Genes
  • Darr, David – Genetically Engineered Mouse Models
  • Day, Emily – Engineering Nanoparticle Architecture to Enable High Precision Cancer Therapy
  • Emanuele, Michael – Ubiquitin Signaling in Cell Cycle and Cancer
  • Frye, Stephen – Academic Drug Discovery and Chemical Biology
  • Gaspar, Rogério – Regulatory Considerations for Nanoformulations and Nanomedicines
  • Hingtgen, Shawn – Stem Cell-Mediated Drug Delivery and Imaging
  • Jiang, Wenlai – Characterization of Nanomaterials
  • Lee, Michael – Drug Development and Early Phase Clinical Trials
  • Luft, Chris – PRINT (Particle Replication in Non-wetting Templates) Nanoparticles
  • Pecot, Chad – What Scientists Can Learn from Clinical Trials in Cancer
  • Perou, Chuck – Cancer Genomics
  • Tropsha, Alex – Computer Modeling of Drug Delivery Systems
  • Veiseh, Omid – Immune Biomodulatory Biomaterials for Cell-Based Therapies
  • Yuan, Hong – Molecular Imaging of Cancer Treatment Response
  • Zamboni, Bill – Pharmacokinetics and Pharmacodynamics of Nanoparticle Agents